当考虑个体差异时,可以在皮层中解码行为
Johan Nakuci1, Jiwon Yeon1,2, Ji-Hyun Kim3
1School of Psychology, Georgia Institute of Technology, Atlanta, GA, United States.
Imaging neuroscience (Cambridge, Mass.)
|August 13, 2025
概括
与反应时间和信心相关的大脑活动在分析个体时,在大脑皮层的大部分区域发现,而不仅仅是几个区域. 这揭示了大脑与行为之间的广泛关系是每个人的独特之处.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 脑部成像 脑部成像
背景情况:
- 传统的小组级分析将行为与有限的大脑区域联系起来.
- 大脑与行为关系的个体变化往往被忽视.
研究的目的:
- 调查像反应时间 (RT) 和信心这样的行为指标是否可以在整个大脑皮层上在特定主体水平上被解码.
- 探索大脑行为映射中的个体差异的程度和性质.
主要方法:
- 利用机器学习模型来解码试验级RT和从执行感知决策任务的50个受试者的大脑激活模式的信心.
- 将大脑皮质分为200个感兴趣的区域 (ROI),并分析了每个主体的解码性能以及在群体层面的解码性能.
- 开发了一种强度测试,需要数百次试验才能获得可靠的解码.
主要成果:
- 集团级解码证实了先前的发现,确定了RT和对小比例ROI (12.0%和3.5%) 的信心.
- 主体级解码显示,经过校正后,RT和信心可以从大多数皮质区域 (分别为90.0%和72.5%) 解码.
- 观察到显著的个体差异,许多区域在各个受试者之间显示出相反的大脑行为关系.
结论:
- 在个体层面上,行为特征在整个皮质中被广泛表现出来,挑战了以前的受约束观点.
- 这项研究强调了考虑团体和个人层面的必要性,以充分理解大脑与行为之间的关系.
- 结果在第二个独立数据集中得到验证.
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