记忆网络之间的内在功能连接性不能预测叙事回忆中的个体差异
Kyle Kurkela1, Maureen Ritchey1
1Department of Psychology and Neuroscience, Boston College, Chestnut Hill, MA, United States.
Imaging neuroscience (Cambridge, Mass.)
|August 13, 2025
概括
大脑连接的差异不能解释健康成年人的个体记忆变化. 在一项大型研究中,默认模式网络中的功能连接无法预测叙事回忆性能.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 脑部成像 脑部成像
背景情况:
- 情节性记忆的个体差异是显著的,但在健康的年轻成年人中了解得很少.
- 情节性记忆被认为涉及在腹部默认模式网络 (DMN-C) 中的功能通信及其与中间叶的连接.
研究的目的:
- 研究DMN-C的内在功能连接性与记忆能力的个体差异之间的关系.
- 探索DMN-C连接是否预测健康年轻人群中叙事回忆任务的表现.
主要方法:
- 利用Cam-CAN数据集中的243名参与者 (18-50岁) 的休息状态,看电影和感官运动任务fMRI数据.
- 估计整个大脑内在的功能连接.
- 应用基于连接组的预测建模 (CBPM) 来识别叙事回忆的预测模式.
主要成果:
- 在DMN-C功能连接 (内在,与其他DMN子网络,或全脑) 和叙事回忆性能之间没有发现显著的关系.
- 探索性CBPM确定了一个预测记忆性能的全脑多变量模式,在很大程度上位于正规记忆网络之外.
结论:
- DMN-C的内在功能连接性不能解释叙事记忆能力的个体差异.
- 记忆性能可能受到大脑连接模式的影响,这些模式超出了传统上被认可的情节性记忆网络.
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