关节前缺血光学神经病在塔卡亚苏的关节炎:一个不祥的系统性标志?
Kaviyapriya Natarajan1, Amit Kumar Deb1, Hemanth Ramachandar1
1Department of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Journal of ophthalmic & vision research
|August 13, 2025
概括
关节前缺血性视神经病变 (AION) 可能是严重的高雅苏动脉炎 (TA) 的早期迹象. 这一案例凸显了TA中AION呈现可能预测快速,积极的疾病进程和不良预后.
科学领域:
- 眼科医生 眼科 眼科
- 类风湿病学 类风湿病学
- 血管医学 血管医学
背景情况:
- 塔卡亚苏动脉炎 (TA) 是一种罕见的,慢性炎症性疾病,影响大动脉,主要是大动脉及其分支.
- 眼部TA的表现可能包括视网膜病变,不太常见的是缺血性视神经病变.
研究的目的:
- 报告一种动脉炎前面缺血性视神经病变 (AION) 的病例,作为严重的塔卡亚苏动脉炎 (TA) 的初始表现.
- 在TA的背景下强调AION的诊断和预后意义.
主要方法:
- 一份病例报告详细介绍了一名34岁的女性患者,突然,痛苦的视力丧失.
- 临床检查, funduscopy 显示Takayasu视网膜病变,和CT 动脉图来确认TA诊断.
- 管理涉及最大的免疫抑制.
主要成果:
- 患者呈现出与AION和塔卡亚苏视网膜病变相一致的症状和眼部发现.
- CT动脉图证实了严重的Takayasu动脉炎.
- 尽管进行了激进的治疗,但患者体验了快速的系统性恶化和死亡率.
结论:
- 动脉前部缺血性视神经病变是一种不常见但显著的Takayasu动脉炎的呈现特征.
- 在TA中出现AION可能预示着疾病的进展过程,并预示着系统性结果不佳.
相关概念视频
Aneurysm II: Clinical Manifestations and Diagnostic Studies
23
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
23
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
38
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
38
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
35
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
35
Glaucoma: Overview
755
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
755
Overview of Systemic Arteries
1.0K
The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
1.0K
Open Angle Glaucoma: Treatment
568
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
568


