由甲状腺休息引起的甲状腺髓癌:一个病例报告
Jacob Beiriger1, Hilary C McCrary1, Patrick Carpenter1
1Department of Otolaryngology - Head and Neck Surgery, University of Utah School of Medicine, 30 N. Mario Capecchi Drive, 4th Floor, Salt Lake City, UT 84112, United States.
Journal of surgical case reports
|August 13, 2025
概括
本病例报告详细介绍了一种罕见的甲状腺髓性癌 (MTC) 病例,这种病例呈现为转移性疾病,而没有明显的原发性甲状腺瘤. 这种诊断在淋巴结中得到证实,该淋巴结起源于异位甲状腺组织的休息.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 甲状腺髓性癌 (MTC) 是一种罕见的神经内分泌瘤,起源于甲状腺C细胞.
- 大多数MTC病例都存在一次性甲状腺病变,使甲状腺外表现不常见.
- 本报告侧重于MTC的一个独特病例,没有甲状腺内原发性瘤的证据.
研究的目的:
- 描述一种罕见的转移性髓性甲状腺癌的病例,源于甲状腺休息.
- 要突出MTC呈现为甲状腺外疾病的诊断挑战.
- 为了对外宫甲状腺组织产生的MTC的有限文献做出贡献.
主要方法:
- 一个67岁的妇女的病例介绍,她有一个子质量,并怀疑患有转移性神经内分泌癌.
- 诊断工作包括PET-CT,细针吸收,切除活检和内分泌评估 (素,CEA).
- 手术干预涉及全甲状腺切除术与中央部剖析,随后进行组织病理学分析.
主要成果:
- 最初的活检表明转移性神经内分泌癌,TTF-1阳性引起肺部起源的怀疑.
- 内分泌检测显示了高西和CEA水平.
- 甲状腺切除术后的病理证实了淋巴结中的转移性MTC,没有证据表明甲状腺内MTC或C细胞激增,支持甲状腺休息的起源.
结论:
- 转移性髓性甲状腺癌可以从异位甲状腺组织 (甲状腺残留物) 出发,而甲状腺中没有明显的原发性瘤.
- 这种表现非常罕见,具有重大诊断和治疗影响.
- 准确的病理审查和全面的内分泌评估对于诊断这种罕见的MTC表现至关重要.
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