有证据表明,左侧和右侧脑网络之间存在补偿关系
Madeline Peterson1, Rodrigo M Braga2, Dorothea L Floris3,4
1Department of Psychology, Brigham Young University, Provo, UT, United States.
Imaging neuroscience (Cambridge, Mass.)
|August 13, 2025
概括
大脑半球显示功能不对称. 这项研究揭示了左侧和右侧脑网络之间的依赖关系,影响了自闭症和精神分裂症等疾病.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 脑部成像 脑部成像
背景情况:
- 人类大脑半球表现出功能不对称,语言网络通常侧向左.
- 其他功能网络中的横向化程度及其相互依赖性在很大程度上仍未被探索.
- 了解网络横向化对于了解神经发育障碍至关重要.
研究的目的:
- 用相对大脑半球表面积来量化17个功能性大脑网络的横向化.
- 测试语言,视觉空间注意力和执行控制网络是否显示出最大的横向化.
- 研究个体内不同功能网络的横向化之间的依赖关系.
主要方法:
- 通过测量相对左脑和右脑半球表面积来量化网络侧面化.
- 检查了基于表面积的横向化测量的有效性和可靠性.
- 在多个大规模神经成像数据集 (HCP,HCP-D,NSD) 中利用相关性矩阵和因子分析.
主要成果:
- 确认了语言网络的显著左侧化和注意力和执行控制网络的显著右侧化.
- 发现了支持依赖关系的证据:一个网络中较大的左侧化与另一个网络中较大的右侧化相关,系统地跨个体.
- 确定了包括语言,注意力和执行控制在内的特定网络,证明了显著的横向化.
结论:
- 大脑功能网络表现出不同程度的横向化,语言,注意力和执行控制网络表现出显著的不对称性.
- 在个体内的不同功能网络的横向化模式之间存在着系统的,依赖的关系.
- 这些发现增强了对宏观大脑组织的理解,并对特征为横向化干扰的神经发育状况产生了影响.
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