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Updated: Sep 11, 2025

Modeling Myotonic Dystrophy 1 in C2C12 Myoblast Cells
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转录基因组变化是1型肌性缩症中代谢功能障碍和肝病的基础

Aono Fukumoto1, Tomoki Yamanaka1, Motoaki Yanaizu2

  • 1Clinical Neurophysiology, Department of Clinical Laboratory and Biomedical Sciences, Graduate School of Medicine, The University of Osaka, 1-7 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Human molecular genetics
|August 13, 2025
PubMed
概括

肌性缩型1型 (DM1) 导致肝功能障碍和脂质异常,由于基因表达和拼接的改变. 缺乏MBNL1蛋白质有助于这些DM1相关的肝脏变化.

关键词:
这就是为什么 MBNL MBNL肝脏 肝脏 肝脏 肝脏 肝脏 肝脏它们是mRNARNA.这里是鼠标鼠标鼠标鼠标鼠标鼠标.肌性发育不良症 肌性发育不良症

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