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Updated: Sep 11, 2025

Removal of an Internal Translational Start Site from mRNA While Retaining Expression of the Full-Length Protein
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Removal of an Internal Translational Start Site from mRNA While Retaining Expression of the Full-Length Protein

Published on: March 16, 2022

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通过转化读透来克服表皮溶解牛皮质中早产终止的治疗机会

Kathleen L Miao1, Ryan Huynh1, David Woodley1

  • 1Department of Dermatology, The Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

Cells
|August 13, 2025
PubMed
概括

阅读疗法为 Epidermolysis Bullosa (EB) 提供了希望,通过恢复由于无意义突变而丢失的功能蛋白质. 研究表明,健美素和新药可以通过使蛋白质产生来改善EB症状.

关键词:
氨基甘油酸氨基化物.皮肤溶解牛皮质的表皮质.这是一种 gentamicin 药物.没有意义的抑制疗法.过早终止的代码子通过阅读治疗治疗.

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