在全身麻醉和神经肌肉阻塞后,定量瞳孔测量的变化
Siddharth Dave1, Chahat Rana2, Jade L Marshall3
1Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, TX.
概括
带有神经肌肉阻塞的全身麻醉显著减缓了瞳孔的速度和反应能力. 定量瞳孔测量 (QP) 显示了神经瞳孔指数的降低和收缩/膨胀速度的改变,表明自主功能发生了变化.
科学领域:
- 麻醉学 麻醉学
- 眼科医生 眼科 眼科
- 神经科学是一个神经科学.
背景情况:
- 定量瞳孔测量 (QP) 提供了标准化的瞳孔评估.
- QP可能有助于监测患有神经肌肉阻塞全身麻醉的患者.
研究的目的:
- 调查全身麻醉与神经肌肉阻塞对定量瞳孔测量 (QP) 值的影响.
- 探索手术过程中瞳孔评估指标的变化.
主要方法:
- 涉及成年手术患者的前性观察性研究.
- 手持式瞳孔计用于麻醉诱导前后的QP读数.
- 每5分钟读取一次,直到20分钟或程序开始.
主要成果:
- 通用麻醉诱导显著减少神经学瞳孔指数,收缩速度,扩张速度和瞳孔大小的百分比变化.
- 在暴露于光线后,收缩的延迟和瞳孔大小显著增加.
- 经过罗库或顺胆的使用后,神经学学生指数没有显著变化.
结论:
- 带有神经肌肉阻塞 (罗库或顺胆) 的全身麻醉导致瞳孔速度和反应能力下降.
- 需要进一步的研究才能充分理解这些QP指标变化的影响.
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