儿童和年轻人的长期COVID:当时和现在
Anna Coughtrey1, Snehal M Pinto Pereira2, Shamez Ladhani3
1UCL GOS Institute of Child Health.
Current opinion in infectious diseases
|August 13, 2025
概括
长期COVID症状在儿童和青少年中持续存在,与成年人不同. 研究强调需要研究儿科长期COVID并开发干预措施.
科学领域:
- 儿童传染病 儿童传染病
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 世界卫生组织于2020年3月11日宣布COVID-19是大流行病.
- 儿童和青少年COVID-19后疾病的临床病例定义在2023年通过专家共识建立.
- 经过五年的流行,对长期COVID的理解仍在不断发展.
研究的目的:
- 在过去五年中,审查了解儿童和青少年长期COVID的关键进展.
- 为了比较和对比长期的COVID症状和特征在儿科和成人群体之间.
- 确定对临床实践和未来研究方向的影响.
主要方法:
- 本综述综合了过去五年发表的研究结果.
- 分析重点是报告的症状,持续时间和儿童和青少年长期COVID的潜在预测因素.
- 考虑与成人长期COVID数据和检测负控进行比较.
主要成果:
- 长期COVID症状在儿童和青少年 (CYP) 感染后可能持续数月.
- 常见的儿科症状包括疲劳,头痛和呼吸短促,在较长的随访中,嗅觉/味觉丧失的频率较低.
- 成年人更常见地报告脑雾和关节/肌肉疼痛;在测试负的对照中也观察到CYP中的许多症状.
- 在CYP中长期COVID的预测因素包括女性性别,喘,过敏,学习困难和家族史.
结论:
- 与成年人相比,长期COVID在儿童和青少年中呈现的不同.
- 在儿科长期COVID中,对身体和心理健康的全面研究至关重要.
- 迫切需要为儿科长期COVID开发有针对性的干预试验.
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