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评分系统和炎症参数与肺炎死亡率之间的关系:急性相反应物指数是新的指数
Emine Sarcan1, Ahmet Burak Erdem1, Sinan Özdemir1
1Ministry of Health, Ankara Etlik City Hospital, Department of Emergency Medicine - Ankara, Turkey.
新的急性阶段反应物指数有效预测社区获得性肺炎的死亡率,超过现有的风险评分. 这个指数显示出作为严重肺部疾病的预后工具的前景.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 生物标志物研究的研究.
背景情况:
- 社区获得性肺炎 (CAP) 具有显著的死亡风险.
- 准确的预后工具对于管理CAP患者至关重要.
- 现有的风险评分和炎症指数在预测农业政策结果方面存在局限性.
研究的目的:
- 调查风险得分,免疫-炎症指数和CAP中的预后之间的关系.
- 评估急性阶段反应物指数 (APRI) 用于预测CAP中的死亡率.
- 将APRI的预测性能与既定分数进行比较.
主要方法:
- 对417名入住第三级医院的CAP患者进行了回顾性研究.
- 收集的人口,临床和实验室数据,包括C-反应蛋白,公素和专蛋白.
- 计算了各种风险得分,免疫-炎症指数,以及新的APRI.
主要成果:
- APRI在预测CAP患者30天死亡率方面表现出很高的准确性.
- 接收器操作特征分析显示,与其他分数相比,APRI在曲线下的面积最高.
- 在1.32的截止值下,APRI准确预测了69.2%的ICU转移患者的死亡率.
结论:
- 与现有的得分和炎症指数相比,APRI是CAP中死亡率的优越预测指标.
- APRI显示出作为高死亡率肺部疾病,包括癌症的预后因素的潜力.
- 该指数提供了一个有价值的工具,用于风险分层和临床决策在CAP管理.
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