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走向含有Psilocybe cubensis真菌生物质的标准化产品

Kimberley Foster¹, Isaac Morrison¹, Shemar Daniel¹

¹Future Wellness, 2 St George's Close, University of the West Indies, Mona.

Journal of AOAC International

|August 13, 2025

概括

种植Psilocybe cubensis可以产生安全的,标准化的生物质供消费. 批量测试psilocybin含量是至关重要的,因为变异性,确保一致的剂量潜在的治疗用途.

科学领域:

菌类学和药物鉴定学
分析化学分析化学
食品安全食品安全

背景情况:

Psilocybe cubensis的果实体有很长的历史用于心理健康.
人们对西和真菌生物质的健康应用重新感兴趣.
目前,全球监管限制限制了这些物质的使用.

研究的目的:

为了评估培养的psilocybe cubensis. 在psilocybin强度的一致性.
为了确定微生物,杀虫剂和重金属污染水平.
为了评估均种植的P. cubensis消费生物质的安全性.

主要方法:

在牙买加,Psilocybe cubensis是在受控的无菌条件下种植的.
用Agilent高性能液体染色学 (HPLC) 分析了三胺含量.
使用各种测定和光谱技术进行了微生物,真菌毒素,杀虫剂和重金属分析.

主要成果:

平均psilocybin和psilocin含量是1.14±0.17%的干量,有显著的批量变化影响剂量.
同质化生物质显示了可接受的污染物水平,表明消费的安全性.
封装生物质保持了稳定的胺含量长达11个月.

结论:

在严格的种植条件下,可以生产适合人类消费的标准化和安全的Psilocybe cubensis生物质.
由于观察到的变异性,强烈建议定期对三胺含量进行批量测试.
这些发现支持P. cubensis在临床试验中作为标准化和安全产品的潜在使用.

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