焦虑症状和相关因素在脊髓灰质炎患者中心干预网络 (SPIN) 队列中的焦虑症状和相关因素:一个横截面研究
Sabrina Provencher1,2, Marie-Eve Carrier1, Gabrielle Virgili-Gervais1
1Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.
Rheumatology (Oxford, England)
|August 13, 2025
概括
与普通人群相比,系统性硬化症 (SSc) 患者的焦虑症状略有增加. 年龄较小,女性性别和某些疾病特征等因素与SSc.的焦虑水平较高有关.
科学领域:
- 类风湿病学 类风湿病学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 系统性硬化症 (SSc) 是一种复杂的自身免疫性疾病,具有显著的心理影响.
- 焦虑是慢性疾病中常见的并发症,但其患病率和SSc中的相关因素需要进一步调查.
研究的目的:
- 将跨国SSc队列中的焦虑症状水平与普通人口进行比较.
- 确定与SSc患者焦虑症状相关的社会人口统计学,生活方式和SSc疾病相关因素.
主要方法:
- 利用了来自于硬化皮肤病患者中心干预网络 (SPIN) 队列的数据.
- 使用患者报告结果测量信息系统 (PROMIS) 评估焦虑2.4a版本焦虑域T分数.
- 采用多变量线性回归来分析焦虑与各种因素之间的关联.
主要成果:
- 在SSc队列 (n=2,463) 中,平均焦虑T分数略高于美国普通人口,但在正常范围内.
- 焦虑症状与年龄较小,女性性别,未婚状况,非白人种族/种族以及居住在加拿大,英国或法国有关.
- 与更高焦虑相关的疾病相关因素包括更高的BMI,症状出现的时间较短,胃肠道参与,关节收缩和Sjögren病.
结论:
- 在患有全身性硬化症的人群中,焦虑症状略有升高.
- 多种社会人口统计学和疾病特异性因素与SSc人口中的焦虑症状有显著的关联.
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