在COVID-19期间的百岁老人死亡率:系统审查和元分析协议
Shaima Ibrahim1, Omnia Mahmoud Abdelraheem1, Wafa Abu El Kheir-Mataria1
1Institute of Global Health and Human Ecology, American University in Cairo, New Cairo, Egypt.
JMIR research protocols
|August 13, 2025
概括
这份系统性审查和元分析检查了百岁以上人群的COVID-19死亡率,强调了公共卫生政策的关键需求,以保护这群脆弱的老年人群在流行病期间.
科学领域:
- 老年学与公共卫生
- 流行病学 流行病学
- 传染病研究 传染病研究
背景情况:
- COVID-19 流行病对老年人造成了不成比例的影响,全球死亡率很高.
- 现有的关于老年人COVID-19死亡率的研究对百岁老人存在知识差距.
- 缺乏对全球COVID-19死亡率的系统审查和元分析,特别是在百岁以上的人群中.
研究的目的:
- 系统地审查和综合全球关于百岁老人中COVID-19死亡率的证据.
- 将百岁老人中的COVID-19死亡率与全球更广泛的老年成人人口进行比较.
- 分析来自各种医疗保健机构的百岁老人和老年人的死亡率数据,包括长期护理机构,医院和家庭环境.
主要方法:
- 在PubMed,Scopus和Web of Science进行了自动化的文献搜索.
- 包括的研究是观察性 (队列和病例控制),使用Joanna Briggs研究所的批判性评估工具进行质量评估.
- 使用R软件对死亡比例进行了元分析,包括异质性评估 (I2值) 和敏感性分析.
主要成果:
- 该审查包括4项研究:3项追溯队列研究和1项观察性,追溯病例控制研究.
- 研究群体的规模差异很大,从不到1000人到超过600万参与者.
- 该元分析综合了来自超过670万老年人的数据,包括百岁老人.
结论:
- 百岁老人代表了在流行病期间高度脆弱的人口,需要有针对性的公共卫生干预措施.
- 为制定有效的公共政策,解决百岁老人死亡率方面的知识差距至关重要.
- 有信息的政策制定可以帮助尽量减少像COVID-19这样的健康危机对人口中老年人群的影响.
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