子油的综合水处理和微生物生物转化为α,ω-二酸
Bashu Dev Pardhe1, Il-Ho Choi2, Chang Hoon Lee3
1Biotechnology Process Engineering Center, KRIBB, 30 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si 28116, Republic of Korea.
Bioresource technology
|August 13, 2025
概括
这项研究将植物油转化为无毒的基,然后由微生物转化为生物基聚合物有价值的二酸. 净化过程产生高纯度的二酸,使可持续的化学生产成为可能.
科学领域:
- 绿色化学 绿色化学
- 生物技术是生物技术.
- 可持续的化学生产
背景情况:
- 有氧化油基生物质需要精炼成碳化合物,以便进行微生物生物转化.
- 用水处理的植物油可以成为生产附加值化学品的可持续原料.
- 阿尔法,欧米茄二酸 (DCAs) 是生物基聚合物合成的关键单体.
研究的目的:
- 通过氧化和微生物生物转化证明水处理植物油通过水氧化和微生物生物转化转化为α,omega-diacids (DCAs).
- 开发一种优化和可扩展的工艺,用于生产高纯度的生物基DCAs.
- 弥合生物原料和绿色化学的工业应用之间的差距.
主要方法:
- 在固定床反应堆中优化了子油的氧化,以生产生物.
- 微生物生物转化n-基 (C6-C18) 成为DCA使用Candida tropicalis.
- 反应蒸和多阶段蒸用于DCAs的分离和净化.
主要成果:
- 在最佳条件下 (370°C,40 bar H2) 的水解氧化产生的高产量 (86.7%) 的生物.
- 通过Candida tropicalis.有效的微生物转化n-基到DCAs (>65g/L,~80%的产量).
- 工业级纯度 (>99%) 通过先进蒸实现了二甲基十二甲基酸盐 (C12) 和二甲基未二甲基酸盐 (C11).
结论:
- 一个可扩展的,两步过程 (氧化和微生物生物转化) 有效地将植物油转化为高纯度的生物基DCAs.
- 这种综合方法促进了可持续化学品生产和生物基聚合物的开发.
- 该研究提供了一个可行的模型,用于在工业化工制造中利用生物资源.
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