产前诊断食道 - - 仍然是一个挑战
Jessica C Pollack1, Leny Mathew2, Clara Williams2
1Division of Pediatric General, Thoracic, and Fetal Surgery, Children's Hospital of Philadelphia, Philadelphia, USA.
Journal of pediatric surgery
|August 13, 2025
概括
胎儿超声波显示在检测食道缩/气管内食道囊 (EA/TEF) 中具有很好的准确性,但灵敏度因类型而异. 产前诊断EA/TEF不会影响产后结果.
科学领域:
- 医学成像医学成像
- 儿科外科手术 儿科外科手术
- 产前诊断 在产前诊断.
背景情况:
- 食道/气管 (EA/TEF) 是一种需要手术修复的先天性异常.
- 准确的产前检测EA/TEF可能会为管理和结果提供信息.
研究的目的:
- 评估胎儿超声波在产前检测EA/TEF中的性能.
- 评估产前诊断对EA/TEF患者产后结果的影响.
主要方法:
- 从2013-2024年对70名怀疑或诊断EA/TEF的患者进行了回顾性审查.
- 队列分析比较产前诊断 (N=28) 与产后诊断 (N=168) 的结果EA/TEF.
主要成果:
- 对EA/TEF的胎儿超声波敏感度为48%,正预测值 (PPV) 为78%.
- 敏感度因EA/TEF类型而异 (36%为C类型,100%为A类型).
- 在对混因素进行调整后,产前和产后诊断组之间在手术时的年龄,出院或重新手术率上没有显著差异.
结论:
- 胎儿超声波对EA/TEF的PPV很高,但灵敏度取决于类型.
- 产前诊断EA/TEF似乎不会改变关键的产后结果.
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