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Updated: Sep 11, 2025

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
07:03

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

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拜卡莱因通过核因子 (erythroid-derived 2) 类似的2通路调节巨细胞铁亡,减轻与代谢功能障碍相关的脂肪肝炎

Yu Wang1, Ying Zhao2, Wenzhi Zhao1

  • 1Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Ministry of Education Key Laboratory of Environment, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Free radical biology & medicine
|August 13, 2025
PubMed
概括

拜卡莱因治疗可通过抑制依赖铁的细胞死亡 (铁亡) 来缓解代谢功能障碍相关的脂肪肝炎 (MASH). 这种天然化合物恢复铁的平衡,并激活Nrf2/FSP1通路,为MASH提供了有前途的治疗方法.

关键词:
在 Baicalein 的酒吧里铁化是铁化的一种.在M1/M2巨细胞中.马什 (MASH) 是一个非常重要的产品.Nrf2 没有任何问题.

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