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从人类到老鼠,再回:在2型糖尿病中岛屿功能障碍的遗传和基因组故事

Romy Kursawe1, Khushdeep Bandesh1, Sai Nivedita Krishnan1,2

  • 11The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA;

Annual review of genetics
|August 13, 2025
PubMed
概括

遗传和基因组研究揭示了参与2型糖尿病 (T2D) 岛屿细胞功能障碍的关键基因和途径. 用各种小鼠模型进行的研究为T2D病理生理学和治疗点提供了新的见解.

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