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相关概念视频

Higher Mental Functions of the Brain: Language01:10

Higher Mental Functions of the Brain: Language

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Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
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Language and Cognition01:27

Language and Cognition

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Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
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Concepts and Prototypes01:24

Concepts and Prototypes

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The human nervous system handles vast amounts of information by translating sensory stimuli into neural impulses, which the brain processes, creating thoughts expressed through language or stored as memories. The brain also synthesizes information from emotions and memories, which significantly influence thoughts and behaviors. This intricate process creates a comprehensive mental picture.
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Models of Health Promotion and Illness Prevention I01:25

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A model is a theoretical way to understand a concept or an idea. Models can overcome barriers to health regardless of diverse economic and cultural backgrounds. In addition, models make the task easier by providing different ways to approach complex issues. There are two major health promotion models: the health belief model and the health promotion model.
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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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In general, a schema is a mental construct consisting of a cluster or collection of related concepts (Bartlett, 1932). There are many different types of schemata, and they all have one thing in common: schemata are a method of organizing information that allows the brain to work more efficiently. When a schema is activated, the brain makes immediate assumptions about the person or object being observed.
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相关实验视频

Updated: Sep 11, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
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大型语言模型驱动的知识图表构建用于心理健康探索.

Shan Gao1, Kaixian Yu2, Yue Yang3

  • 1Yunnan Key Laboratory of Statistical Modeling and Data Analysis, Yunnan University, Kunming, Yunnan, China.

Nature communications
|August 13, 2025
PubMed
概括

我们开发了心理障碍知识图 (MDKG),以整合分散的心理健康研究. 这种新的资源加速了精神病学发现,并通过揭示超过100万个新的关联来改善临床见解.

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相关实验视频

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Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
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科学领域:

  • 计算生物学是一种计算生物学.
  • 精神病学信息学 在精神病学信息学.
  • 知识表示知识表示.

背景情况:

  • 心理健康研究结果分散在各种研究和数据库中.
  • 这种碎片化阻碍了对心理健康知识的全面理解和临床应用.
  • 现有的资源缺乏高级分析所需的规模和上下文化.

研究的目的:

  • 为精神障碍创建一个大规模的,上下文化的知识图 (MDKG).
  • 通过使用大型语言模型,统一来自生物医学文献和策划数据库的证据.
  • 为了实现更细微的解释和加快精神病学研究.

主要方法:

  • 使用大型语言模型构建MDKG来处理生物医学文献和数据库.
  • 纳入超过1000万个关系,包括近100万个新的协会.
  • 编码了诸如条件,人口统计和临床属性之类的上下文特征.

主要成果:

  • MDKG包含超过1000万个关系,几乎有100万个新的关联.
  • 对上下文特征的结构编码使微妙的解释和专家验证成为可能,减少了高达70%的评估时间.
  • 在英国生物银行数据中,MDKG增强的表示显著改善了多种精神障碍的预测性能.

结论:

  • MDKG为心理健康研究提供了一个可扩展的,语义上丰富的资源.
  • 知识图为加速发现和可解释的数据驱动的临床见解提供了便利.
  • MDKG代表了整合和利用复杂的心理健康数据的重大进步.