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减肥手术后的脏结果:基于人口的队列研究
Christian Goul Sørensen1, Simon Kok Jensen2, Reimar Wernich Thomsen2
1Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Olof Palmes Allé 43-45, 8200 Aarhus N, Denmark. christiangoul1995@gmail.com.
BMC nephrology
|August 14, 2025
概括
减肥手术增加了急性损伤 (AKI) 和结石的风险,但与仅肥胖相比,降低了慢性病 (CKD) 和衰竭的长期风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 腹部外科 腹部外科
- 公共卫生 公共卫生
背景情况:
- 肥胖与慢性病 (CKD) 有关.
- 腹腔外科手术可以改善与肥胖相关的CKD,但可能增加急性损伤 (AKI) 和高氧流的风险.
- 减肥手术后的脏结果需要检查.
研究的目的:
- 为了研究腹手术后的脏结果.
- 为了比较腹部外科手术后的AKI,结石,CKD和衰竭的风险,与匹配的对照对照进行替代疗法 (KFRT).
主要方法:
- 基于人口的登记册研究在丹麦 (2006-2018).
- 包括经过Roux-en-Y胃绕道 (RYGB) 或袖子胃切除术 (SG) 的个人.
- 年龄和性别匹配的1: 5比较与肥胖但没有腹部手术的个体;分析了风险并使用了Cox回归.
主要成果:
- 包括18,827名减肥手术患者和94,135名对照患者;随访时间中位数为8.1年.
- 一年的AKI风险为2.7%;十年的风险:腎 3.5%,CKD 0.4%,KFRT 0.2%.
- 腹腔外科手术与AKI (1.63) 和石病 (1.73) 的调整HR增加有关,但对CKD (0.41) 和KFRT (0.63) 的HR降低.
结论:
- 腹腔外科手术与较高的AKI和结石病的短期风险有关.
- 与匹配的肥胖个体相比,腹手术后慢性病和功能衰竭的长期风险降低了.
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