系统性免疫炎症指数 (SII) 在诊断儿科急性尾炎中的作用
Binali Firinci1, Cetin Aydin1, Dilek Yunluel1
1Department of Pediatric Surgery, Medical Faculty of Ataturk University, 25100 Erzurum, Turkey.
系统性免疫炎症指数 (SII) 准确诊断儿童急性尾炎. 这种易于获得的生物标志物还有助于检测复杂的病例,提高了儿科诊断的准确性.
科学领域:
- 儿科手术 儿科手术
- 临床诊断 临床诊断 临床诊断
- 炎症生物标志物 炎症生物标志物
背景情况:
- 在儿童中诊断急性尾炎是具有挑战性的,因为症状重叠和诊断工具的限制.
- 系统性免疫炎症指数 (SII) 在成年人中表现有前途,但其儿科实用性尚不清楚.
- 评估SII对儿科尾炎和复杂病例预测的准确性至关重要.
研究的目的:
- 评估SII在儿科急性尾炎的诊断准确性.
- 确定SII对儿童复杂尾炎的预测值.
- 将SII与NLR和PLR等其他炎症指数进行比较.
主要方法:
- 对397名儿科患者 (5-15岁) 的回顾性研究.
- 包括297例确诊的尾炎病例和100例对照病例.
- 计算了SII,NLR,PLR;对诊断性能进行了ROC分析.
主要成果:
- 在尾炎患者中,SII显著更高 (中位数为2218.4比356.3).
- 尾炎的诊断准确性很好 (AUROC=0.95),敏感度为91%,特异性为88%.
- 对于复杂的尾炎,SII的准确性中等 (AUROC=0.66),敏感度为83%.
结论:
- SII是诊断儿科急性尾炎的可靠生物标志物.
- SII可以帮助早期发现复杂的尾炎病例.
- 整合SII可能会提高诊断精度,特别是在资源有限的环境中.
更多相关视频
08:51Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
15:49Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
相关概念视频
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Inflammatory Response I: Vascular and Cellular
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
