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Updated: Sep 11, 2025

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亲和关系通过目标介导的药物处置影响抗GD2抗体的功能强度

Sascha Troschke-Meurer1, Maxi Zumpe1, Peter Moritz Ahrenberg1

  • 1Department of Pediatric Oncology and Hematology, University Medicine Greifswald, 17475 Greifswald, Germany.

Cancers
|August 14, 2025
PubMed
概括

在神经母细胞瘤模型中,dinutuximab beta (DB) 与naxitamab (NAXI) 相比,表现出优异的抗体依赖细胞细胞毒性 (ADCC). 这种增强的功效与naxitamab有关.

关键词:
基于GD2的免疫疗法.抗体结合亲和力 抗体结合亲和力迪努杜西马布ββ的使用情况纳克西塔马巴的情况神经母细胞瘤的神经母细胞瘤目标介导的药物处置是指通过目标介导的药物处置.

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