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在被诊断为癌症的人群中,优化运动来管理化疗诱导的外周神经病变
Dhiaan Sidhu1, Jodie Cochrane Wilkie1,2, Jena Buchan1
1Physical Activity, Sport and Exercise Research Theme, Faculty of Health, Southern Cross University, Gold Coast 4225, Australia.
Cancers
|August 14, 2025
概括
运动,特别是多式模式的项目,有效地管理化疗诱导的周围神经病变 (CIPN). 本综述为临床医生提供实用指导,帮助他们将运动纳入患者护理,改善症状和生活质量.
科学领域:
- 在瘤学瘤学.
- 神经学 神经学
- 康复医学 康复医学 康复医学
背景情况:
- 化疗诱导的周围神经病变 (CIPN) 是癌症护理的一个重大挑战,往往限制治疗坚持和患者的生活质量.
- 虽然运动是CIPN的一个有希望的干预措施,但其临床应用受到缺乏对医疗保健专业人员明确,可访问的指导的阻碍.
研究的目的:
- 系统地审查现有的关于管理CIPN的炼干预措施的研究.
- 为临床医生提供基于证据的实用建议,将运动纳入标准患者护理方案.
主要方法:
- 在主要数据库 (MEDLINE,CINAHL,SPORTDiscus) 中使用相关关键字进行了全面的文献搜索.
- 选择了11项符合纳入标准的高质量研究 (接受神经毒性化疗的CIPN成年人),并使用JBI批判性评估工具进行了批判性评估.
- 数据提取侧重于研究设计,参与者人口统计,炼干预措施和报告结果.
主要成果:
- 十一项研究评估了各种运动类型,包括多式运动,,有氧运动,抵抗,平衡和感觉运动.
- 多模式运动干预表明,CIPN症状严重程度,患者功能和整体生活质量显著改善 (p <0.05).
- 包括的研究具有高的方法质量,随机对照试验得分为9-11/13和准实验研究得分为8/9的评估工具.
结论:
- 运动,特别是多式联动的方法,为患有CIPN的患者提供了巨大的好处.
- 这一审查为临床医生实施炼策略提供了基础,解决了对可访问的患者管理指南的关键需求.
- 建议进行进一步的研究,以优化运动处方,并为CIPN管理制定标准化的临床指南.
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