在手术治疗恶性胃出道阻塞的进展
Sang-Ho Jeong1, Miyeong Park2, Kyung Won Seo3
1Department of Surgery, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon 51472, Republic of Korea.
Cancers
|August 14, 2025
概括
恶性胃出口阻塞 (MGOO) 越来越常见,需要不同的治疗方法. 本综述比较了内镜支架,手术和EUS引导的胃肠静脉术,以获得最佳的患者结果.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 干预性内镜检查是干预性的内镜检查.
背景情况:
- 恶性胃出口阻塞 (MGOO) 是晚期胃癌和胰腺癌的严重并发症.
- 恶性瘤是胃出口阻塞 (GOO) 的主要原因,占全球病例的50-80%.
- 由于口服摄入量受损和胃肠道症状,MGOO显著影响患者的生活质量.
研究的目的:
- 审查MGOO的病理生理学,流行病学和治疗方法.
- 为了比较各种MGOO治疗选择的疗效和结果.
- 强调MGOO患者个性化,多学科的治疗选择的重要性.
主要方法:
- 关于MGOO的病理生理学,流行病学和治疗的文献综述.
- 治疗方法的分析,包括保守的管理,内镜支架,手术性胃支架 (GJ),胃分割胃支架 (SPGJ) 和内镜超声波导向胃肠支架 (EUS-GE).
- 基于侵入性,症状缓解,再阻塞率和长期息的治疗结果的评估.
主要成果:
- 内镜支架提供快速缓解,但具有更高的再阻塞率.
- 像GJ和SPGJ这样的手术选择提供更持久的息,特别是在预后较长的患者中.
- 与传统的GJ相比,SPGJ显示了减少延迟胃排空和改善口服摄入的潜力.
- EUS-GE是一个有前途的最小侵入性选择,结合了耐用性和效率,尽管长期数据尚未公布.
结论:
- 对MGOO的治疗选择需要仔细考虑患者的因素,瘤特征,预后和可用的资源.
- 个性化,多学科的决策对于优化MGOO的症状管理,营养状况和整体结果至关重要.
- 需要进一步的研究,特别是EUS-GE的长期数据,以完善MGOO的治疗策略.
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