在老年人中补充白的效果与萨尔科佩尼亚:一个元分析
Chienhsiu Huang1, Min-Hong Hsieh2,3
1Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin Town 622401, Taiwan.
Nutrients
|August 14, 2025
概括
氨酸补充剂可能会在老年人肉类症患者的肌肉力量和身体功能上略有改善. 然而,当单独使用时,它的有效性是有限的,这表明组合疗法可能更有益.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 肌肉生理学 肌肉生理学
背景情况:
- 关于白对老年人肉症的影响的研究有限,结果相互矛盾.
- 标志着肌肉损失的萨尔科佩尼亚会影响老年人,影响他们的行动能力和健康.
- 现有的关于氨酸补充剂治疗肉症的研究需要合成来澄清其有效性.
研究的目的:
- 进行一项元分析,评估白补充剂对老年人肉症相关参数的影响.
- 从现有文献中整合数据,以确定白对肌肉力量,质量和身体表现的影响.
主要方法:
- 十项随机对照试验和一项前性研究的元分析.
- 纳入标准:65岁以上的参与者参加了关于老年人肉病的欧洲工作组的会议.
- 测量结果包括握力,尾骨肌肉质量/身高2,步行速度和短时间的体力表现电池.
主要成果:
- 与安慰剂相比,素补充剂显著改善了手握强度 (p=0.03),尾骨肌肉质量/高度2 (p=0.02) 和步行速度 (p=0.008).
- 服用高剂量的白氨酸显著改善了尾骨肌肉质量/身高2 (p=0.02) 和步行速度 (p=0.01).
- 结合白和维生素D显著改善了尾骨肌肉质量/身高2 (p=0.03) 与对照组相比.
结论:
- 低质量的证据表明,氨酸补充剂可能会改善老年人肌肉强度,质量和身体表现.
- 当作为唯一的干预措施使用时,氨酸对萨尔科佩尼亚的治疗益处似乎有限.
- 与氨酸并发的同时治疗可能会提高其在治疗老年人肉类的有效性.
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