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作为口腔皮肤再生剂的希比斯克原蛋白替代品 (VC-H1):一个为期12周的试点研究
Yujin Baek1, Ngoc Ha Nguyen1,2, Young In Lee1,3
1Department of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
International journal of molecular sciences
|August 14, 2025
概括
虫酶提取物 (VC-H1) 补充剂显著改善了皮肤水分,弹性,并减少了光衰老个体的纹. 这种植物性原蛋白替代品显示出对皮肤再生的承诺.
科学领域:
- 皮肤病学 皮肤病学
- 营养保健品 营养保健品
- 化品 化品 化品
背景情况:
- 皮肤衰老的特点是水分减少,弹性降低,纹增加.
- 口服原蛋白补充剂的安全问题引发了对植物替代品的兴趣.
- Hibiscus sabdariffa 具有抗氧化和抗衰老特性,但临床数据有限.
研究的目的:
- 评估植物性原蛋白替代品 (VC-H1,Hibiscus酶提取物) 在皮肤衰老参数上的疗效.
- 评估VC-H1对皮肤水分的影响,皮肤间的水分流失 (TEWL),弹性和纹.
- 为了比较VC-H1与安慰剂在照相老化个体的影响.
主要方法:
- 一个为期12周的随机,双盲,安慰剂对照试验.
- 98名皮肤干燥和脑周纹的参与者 (35-60岁) 每天接受1.5g的VC-H1或安慰剂.
- 在基线,6周和12周测量了皮肤水分,TEWL,深度水分,角质素指数,弹性和纹参数.
主要成果:
- VC-H1显著增加了皮肤水分和深层水分含量.
- 在VC-H1组中观察到TEWL和角质素指数的降低.
- 随着VC-H1补充,人们注意到纹深度和皮肤弹性的显著改善.
结论:
- 口服VC-H1补充剂有效改善了皮肤衰老的关键指标.
- VC-H1证明了作为传统原蛋白补充剂的可行的植物性替代品的潜力.
- 这项研究支持使用Hibiscus sabdariffa提取物用于皮肤复发.
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