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Updated: Sep 11, 2025

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
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在生殖线ATM突变黑色素瘤中评估对PARP抑制反应的决定因素

Eleonora Allavena1,2, Michela Croce3, Bruna Dalmasso2

  • 1Department of Internal Medicine and Medical Specialties, University of Genoa, 16132 Genoa, Italy.

International journal of molecular sciences
|August 14, 2025
PubMed
概括

有害的ATM变体和同源重组缺陷 (HRD) 并没有预测黑色素瘤中PARP抑制剂 (PARPi) 敏感性. 沉默SLFN11有助于耐药性,这表明需要全面的方法来有效治疗黑色素瘤.

关键词:
这是一个ATMATMATM.人力资源副主任HRD在巴黎的巴黎.生殖线变异的细菌变化黑色素瘤是一种黑色素瘤.

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