肥胖是孕妇患血栓的危险因素之一
Daria Korolova1, Andrea Suranyi2, Anastasiia Pavlenko1
1Palladin Institute of Biochemistry of NAS of Ukraine, 01054 Kyiv, Ukraine.
Journal of clinical medicine
|August 14, 2025
概括
怀孕期间的肥胖会增加血栓形成风险标志物,特别是在妊娠的第三季度. 这些标志物在肥胖的孕妇中更早出现,这表明血栓性并发症风险增加.
科学领域:
- 产科和妇科 产科和妇科
- 血液学 血液学 血液学
- 公共卫生 公共卫生
背景情况:
- 怀孕自然会增加血凝因子,增加血栓形成的风险.
- 肥胖进一步加剧了这种风险,造成了严重的健康问题.
- 了解肥胖孕妇的血栓形成标志物对于预防至关重要.
研究的目的:
- 为了评估不同体重指数 (BMI) 的孕妇的血栓形成风险标志物.
- 为了比较肥胖和非肥胖的孕妇之间的血栓形成风险标志物水平.
- 为了确定妊娠阶段和肥胖对这些标记物的影响.
主要方法:
- 研究包括97名健康的孕妇 (18-42岁),没有接受抗血栓治疗.
- 参与者根据孕期BMI分组:≤25 (n=42) 和>25 (n=55).
- 为了进行比较,包括了10名非怀孕,非肥胖妇女的对照组.
主要成果:
- 纤维素水平随着怀孕增加,比BMI更多.
- 肥胖妇女在妊娠第三季度的D-二聚物水平较高.
- 可溶性纤维素和血小板聚合减少与D-二次体相关,表明肥胖孕妇的血栓形成增加.
结论:
- 血栓形成风险标志物在第三个三个月内显著积累.
- 肥胖和超重的孕妇显示早期的标志物积累.
- 怀孕期间的肥胖与更高的血栓性并发症风险有关.
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