分析COVID-19的心率变化,使用持续信号处理技术预测ICU死亡率.
Guilherme David1, André Lourenço1,2, Cristiana P Von Rekowski1,3,4
1ISEL-Instituto Superior de Engenharia de Lisboa, Instituto Politécnico de Lisboa, Rua Conselheiro Emídio Navarro 1, 1959-007 Lisbon, Portugal.
Journal of clinical medicine
|August 14, 2025
概括
对心电图信号的短期心率变化 (HRV) 分析可以预测ICU的COVID-19患者的住院死亡率. 这种非侵入性方法有助于早期风险分层和及时的治疗决策.
科学领域:
- 关键护理医学 关键护理医学
- 心脏病学 心脏病学
- 数据科学数据科学数据科学
背景情况:
- 心率变化 (HRV) 已被探索用于预测疾病和死亡率,但最佳特征仍未定义.
- 随着COVID-19的流行,重症患者的早期死亡率预测变得越来越重要.
- 来自ICU入院的ECG信号为HRV分析提供了一个潜在的窗口.
研究的目的:
- 调查HRV分析的潜力,用于早期预测COVID-19 ICU患者的住院死亡率.
- 确定最佳的HRV特征和风险分层的分析方法.
主要方法:
- 追溯观察性研究分析了82名COVID-19ICU患者的ECG信号.
- 在各种观察间隔中使用滑动窗口提取的HRV指数.
- 应用特征选择,减少技术和分类模型 (包括LDA,梯度增强,随机森林).
主要成果:
- 在患者窗口中编译特征平均值 (方法D) 产生了最佳的预测性能.
- 线性差异分析 (LDA) 显示出一致和强大的性能,AUC达到0.82±0.13.
- 其他模型,如渐变增强和随机森林,也显示出高的预测准确度.
结论:
- 短期HRV分析是一种可行且具有临床相关性的非侵入性工具,用于重症监护中的早期风险分层.
- 这种数据驱动的方法可以指导高风险的ICU患者及时做出治疗决策.
- 通过积极的患者管理,有可能减少住院死亡率.
更多相关视频
相关概念视频
Pulse rhythm
927
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
927
Correlation between ECG and Cardiac Cycle
8.4K
The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
8.4K
Factors Influencing Heart Rate
4.6K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
4.6K
Pulse Oximetry
413
Pulse oximetry, or SpO2, is a non-invasive method for continuously monitoring arterial oxygen saturation (SaO2). This procedure involves attaching a probe or sensor to the patient's fingertip, forehead, earlobe, or nose bridge. The sensor works by detecting changes in oxygen saturation levels through light signals generated by the oximeter and reflected by the pulsing blood under the probe.
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
413
ECG Interpretation of Rhythms
3.9K
An electrocardiogram (ECG)graphically represents the heart's electrical activity on ECG paper or a monitor.
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
3.9K
Cardiac Output I:Effect of Heart Rate on Cardiac Output
1.3K
Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
1.3K


