社区获得性肺炎住院患者的身体组成变化
Ryuji Sugiya1, Osamu Nishiyama2, Masashi Shiraishi3
1Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya 4618673, Japan.
Journal of clinical medicine
|August 14, 2025
概括
社区获得性肺炎 (CAP) 的住院治疗在老年人中显著降低了体重和骨肌肉 (SM). 低血清蛋白质水平预测了更大的SM损失,突出显示了康复期间需要营养支持的需要.
科学领域:
- 老年学是一门学科.
- 临床营养学 临床营养学
- 肺部病理学 肺部病理学
背景情况:
- 社区获得性肺炎 (CAP) 住院期间的身体组成变化没有得到充分记录.
- 住院可能会对营养状况和身体成分产生负面影响.
研究的目的:
- 研究住院对CAP患者体质组成的影响.
- 为了确定CAP住院期间身体组成变化的预测因素.
主要方法:
- 对64名住院患有CAP的患者进行前性队列研究.
- 生物电阻分析用于在入院24小时内和出院前测量身体组成 (体重,BMI,脂肪质量,骨肌肉).
- 统计分析以确定身体组成变化和入院变量之间的关联.
主要成果:
- 观察到体重,体重指数 (BMI),骨肌肉 (SM),SM指数,无脂肪质量 (FFM) 和FFM指数 (p < 0.001) 的显著下降.
- 脂肪质量 (FM) 和FM指数没有显著变化.
- 低血清总蛋白水平独立预测了SM指数的更大下降 (p = 0.004).
结论:
- 住院治疗CAP导致体重和MS显著减少,主要是由于肌肉损失.
- 在入院时血清总蛋白低的患者有较高的加速SM指数下降风险.
- 营养干预和康复对于在住院期间和住院后管理CAP患者至关重要.
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