提高Boesenbergia rotunda生物活性化合物的稳定性:通过喷雾干燥进行微封装及其物理化学评估
Fahmi Ilman Fahrudin1, Suphat Phongthai2, Pilairuk Intipunya2,3
1Doctoral Degree Program in Food Science and Technology, Chiang Mai University, Chiang Mai 50100, Thailand.
Foods (Basel, Switzerland)
|August 14, 2025
概括
喷雾干燥指根提取物与马尔托德克斯特林和阿拉伯改善了粉末的特性. 1:1比率产生了具有出色溶解性和稳定性的微囊,适合食品和营养药物用途.
科学领域:
- 食品科学与技术 食品科学与技术
- 制药科学 制药科学
- 自然产品化学 自然产品化学
背景情况:
- 波森伯吉亚轮 (指根) 含有有价值的生物活性化合物.
- 提取物在食品和营养药物应用中经常面临稳定性和处理挑战.
- 微封装提供了一种方法来保护和改善植物提取物的输送.
研究的目的:
- 通过喷雾干燥,使用马尔托德克斯特林和阿拉伯微封装Boesenbergia旋转提取物.
- 优化墙壁材料比率,以改善物理化学性能和生物活性化合物保留.
- 评估微封装对粉末特性和稳定性的影响.
主要方法:
- 喷雾干燥被用来封装指根提取物,其中的马尔托德克斯:阿拉伯比例各不相同 (1:0,0:1,1:1, 2:1, 1:2).
- 分析了微囊的形态 (SEM),颗粒大小,流动性,湿度,高度,可溶性,封装效率和生物活性化合物保留 (pinostrobin,pinocembrin).
- 使用TGA/DSC评估了热稳定性.
主要成果:
- 1:1的马尔托德克斯特林:阿拉伯比率 (MD1GA1) 导致微囊具有高溶解性 (98.70%),低湿度 (8.69%),低湿度 (5.08%) 和均形态.
- 扫描电子显微镜 (SEM) 显示,在富含马尔托德克斯的配方中,表面痕较少的球形颗粒.
- 所有配方都保留了皮诺斯特罗宾和皮诺塞姆林,皮诺斯特罗宾的稳定性更高.
结论:
- 使用马尔托德克斯特林和阿拉伯进行微封装,有效地改善了指根提取物的物理化学特性.
- MD1GA1配方提供了一个平衡的理想特征,包括良好的溶解性和稳定性.
- 由此产生的微囊由于其增强的稳定性和处理性,有望在食品和营养药品行业应用.
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