增加饮食中可消化的蛋白质可能会加剧 brojler 的菌病
Jung Yeol Sung1,2, Olayiwola Adeola1
1Department of Animal Sciences, Purdue University, West Lafayette 47907, IN, USA.
Animal nutrition (Zhongguo xu mu shou yi xue hui)
|August 14, 2025
概括
高消化不易的蛋白质饮食会使肉中的菌病恶化,减少体重增加和的消化能力. 这种饮食还降低了在感染期间的杯细胞和紧结蛋白表达.
科学领域:
- 动物科学动物科学
- 禽类的营养 养
- 鸟类病理学 鸟类病理学
背景情况:
- 菌病是肉中的一种严重的寄生虫病.
- 饮食中的蛋白质度会影响肠道健康和疾病抵抗力.
- 难以消化的蛋白质可能会对肠道完整性和营养利用产生负面影响.
研究的目的:
- 调查饮食中可消化蛋白的增加是否会加剧 brojler chickens 中的菌病.
- 评估菌体挑战和高消化蛋白对生长性能和肠道健康的综合影响.
- 评估对肠道消化能力,杯状细胞形态和炎症基因表达的影响.
主要方法:
- 一个2x2的因数设计,有192只肉,涉及菌挑战 (Eimeria物种) 和饮食治疗 (标准与高消化蛋白).
- 自化家禽粉用于增加不可消化的蛋白质含量.
- 测量包括体重增加,料摄入量,阴茎中的消化能力,阴茎杯细胞数量和阴茎基因表达 (TNF-α,IL-1β,occludin).
主要成果:
- 高消化不易的蛋白质加剧了体重减轻,特别是在受挑战的鸟类 (P < 0.05).
- 菌挑战和高消化性蛋白质都降低了叶内的消化能力 (P < 0.05).
- 一个相互作用显示,挑战性鸟类中高消化蛋白的杯细胞减少 (P <0.05),而挑战性鸟类的炎症基因表达增加,高消化蛋白减少了occludin mRNA.
结论:
- 增加饮食中不可消化的蛋白质可以加剧肉中菌病的负面影响.
- 高消化性蛋白质饮食会损害肠道屏障功能,由减少杯状细胞和奥克卢丁表达体现出来.
- 饮食策略应考虑不可消化的蛋白质水平,以减轻菌病的影响.
相关概念视频
Overview of Protein Metabolism
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Dysbiosis of the Gut Microbiota
The human gut microbiome includes a diverse array of microbial species, including beneficial commensals and opportunistic pathogens, which interact to support host health. These microbes contribute to essential functions such as nutrient metabolism, immune system modulation, and maintenance of intestinal barrier integrity. However, disruptions to this equilibrium—referred to as dysbiosis—can have widespread physiological consequences.Dysbiosis is often characterized by reduced microbial...
Giardiasis
Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Inflammatory Bowel Disease III: Crohn's Disease
Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...


