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评估图像质量和异质预测值的读出细分的回声平面成像的扩散权重直肠MRI的评估

Mingrui Song¹, Yichuan Liang¹, Huiying Wang¹

¹Department of Radiology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.

Frontiers in oncology

|August 14, 2025

概括

读出细分的回声平面成像 (rs-EPI) 与单次回声平面成像 (ss-EPI) 相比,在扩散权重 (DWI) 的直肠MRI中提供更优质的图像质量. 两种DWI技术的明显扩散系数 (ADC) 值同样预测瘤侵略标记.

科学领域:

放射学放射学是一门学科.
在瘤学瘤学.
医疗成像医学成像

背景情况:

扩散权重成像 (DWI) 对于直肠癌 (RC) 评估至关重要.
将读出分段的回声平面成像 (rs-EPI) 和单拍回声平面成像 (ss-EPI) 进行比较,对于优化DWI质量至关重要.
了解表面扩散系数 (ADC) 的预测值是治疗分层的关键.

研究的目的:

为了从质量和数量上比较rs-EPI和ss-EPI之间的图像质量,用于DWI直肠MRI.
评估从两种DWI技术中得出的ADC值的异质预测值.
为了将ADC值与瘤侵略标志物如Ki-67和HIF-1α相关联.

主要方法:

对 rs-EPI 和 ss-EPI 的损伤度,正常结构显示,整体图像质量,几何扭曲和解剖学差异的主观评估.
信号与噪声比率 (SNR),对比率 (CR) 和对比度与噪声比率 (CNR) 的客观比较.
用皮尔森的相关性和ROC分析来评估ADC值和Ki-67/HIF-1α之间的关系.

主要成果:

与ss-EPI相比,rs-EPI显示了明显更高的损伤度,正常结构显示,整体图像质量和减少的几何扭曲 (P<0.001).
rs-EPI也显示出优异的SNR,CNR和CR (P<0.001),而ADC值在技术之间是可比的.
ROC分析显示,使用rs-EPI和ss-EPI的ADC,高Ki-67和HIF-1α表达的预测值相似 (AUC在0.77-0.82之间).

结论:

与ss-EPI相比,rs-EPI DWI在直肠MRI中显著提高了图像质量.
通过rs-EPI和ss-EPIDWI获得的ADC值同样与瘤侵略的病理标志物有关.

关键词:

在 Ki-67 机器人扩散权重成像技术的使用.缺氧诱导的因素-1αα.图像质量图像质量预测价值是一个预测值.读出细分的回声平面成像.一次射击回声平面成像

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