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Single-cell Gene Expression Using Multiplex RT-qPCR to Characterize Heterogeneity of Rare Lymphoid Populations
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根据单细胞RNA测序元分析,免疫疾病对话的基因基因细胞通信

Mouly F Rahman1, Andre H Kurlovs1, Munender Vodnala1

  • 1Precision Medicine and Computational Biology, Sanofi US, Cambridge, MA, United States.

Frontiers in systems biology
|August 14, 2025
PubMed
概括

这项研究使用单细胞RNA测序分析了各种疾病中的免疫细胞通信. 它确定了驱动免疫细胞迁移的关键相互作用,为治疗炎症和自身免疫疾病提供了新的点.

关键词:
细胞通信是细胞通信.这是一种化学物质,chemokine.这是一种extravasation.免疫疾病是一种免疫疾病.这是一个元分析.这就是scRNA-seqq.

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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...