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检查点免疫疗法与MDS中瘤抗原特异性CD4+ T细胞的优先激活有关

Elizabeth A Griffiths1, Pragya Srivastava1, Eduardo Cortes Gomez2

  • 1Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY.

Blood neoplasia
|August 14, 2025
PubMed
概括

结合NY-ESO-1疫苗接种与骨髓质疏松症候群 (MDS) 中的迪西他和尼沃卢马布,产生了抗原特异性T细胞反应,但揭示了树突细胞功能的缺陷,影响了免疫疗法的有效性.

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