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Updated: Sep 11, 2025

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在PD-L1-阴性肺腺癌中,TF-1表达分层化疗免疫疗法的益处:一个现实世界的生物标志物验证

Ning Yang1, Lijuan Xiong2, Ya Guo3,4

  • 1Department of Oncology, General Hospital of Southern Theater Command, Guangzhou, China.

Journal of thoracic disease
|August 14, 2025
PubMed
概括

甲状腺转录因子-1 (TTF-1) 表达可以预测编程死亡配体1 (PD-L1) 阴性肺腺癌的免疫治疗反应. TTF-1-阴性患者从化疗免疫疗法中受益,而TTF-1-阳性患者的生存率没有改善.

关键词:
甲状腺转录因子-1 (TTF-1)化学免疫疗法 化学免疫疗法肺部腺癌瘤是什么?编程死亡链条1 (PD-L1) 编程死亡链条1 (PD-L1)

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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