单次和多次饮食维生素暴露与心力衰竭风险之间的关联:一个横截面研究
Jiashun Huang1,2, Feifei Zhong1,2, Bo Liu1,2
1Department of Cardiovascular Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Journal of thoracic disease
|August 14, 2025
概括
饮食中摄入更多的维生素A,K,B1和B2与心力衰竭 (HF) 的风险降低有关. 这项研究强调了特定维生素在HF预防策略中的潜在作用.
科学领域:
- 心血管疾病流行病学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 心力衰竭 (HF) 是一种广泛的心血管疾病,与饮食维生素消费有复杂的联系.
- 了解这些关联对于制定有效的HF预防和管理策略至关重要.
研究的目的:
- 调查单种和多种维生素的饮食摄入量与患心力衰竭的风险之间的关系.
- 为预防HF的营养干预提供基于证据的基础.
主要方法:
- 利用了2009-2014年国家健康和营养检查调查 (NHANES) 的数据.
- 采用对共变量调整的模型来分析维生素A,C,D,K,B6,B12,B1和B2摄入量与HF风险之间的关联.
- 应用限制立方线 (RCS) 分析来评估剂量反应关系.
主要成果:
- 该研究包括13,025名参与者 (12,623名非高频,402名高频).
- 在HF组中观察到维生素A,K,B6,B1和B2的摄入量较低.
- 增加维生素A,K,D,B12,B1和B2的摄入量与HF风险有负面关联 (ORs从0.673到0.750不等).
- 在维生素K,B6,B1,B2摄入量和降低HF风险之间发现了线性相关性.
结论:
- 饮食中摄入更多的维生素A,K,B1和B2与心力衰竭风险降低有关.
- 维生素K,维生素B6,维生素B1和维生素B2的摄入量与HF发病率之间存在负相关性.
- 这些发现支持特定的饮食维生素在减轻HF风险方面的作用.
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