相关实验视频
Updated: Sep 11, 2025
03:22
Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
868
与IgG4相关的疾病和胸腔溢液:系统性审查
Honorio J Martínez-Martínez1, Lucía Ferreiro1,2, Elisa Landín1
1Pulmonology Department, University Clinical Hospital of Santiago de Compostela, Santiago de Compostela, Spain.
Journal of thoracic disease
|August 14, 2025
概括
这项研究描述了免疫球蛋白G4相关疾病 (IgG4-RD) 中的膜溢出,发现它通常影响老年男性,对皮质类固醇有很好的反应. 胸腔液通常是一种淋巴细胞排泄物,具有升高的腺脱氨酶.
科学领域:
- 肺部病理学 肺部病理学
- 类风湿病学 类风湿病学
- 病理学 病理学 病理学
背景情况:
- 免疫球蛋白G4相关疾病 (IgG4-RD) 是一种罕见的纤维炎症疾病.
- 胸腔溢液 (PE) 仅在4%的IgG4-RD病例中发生,其特征以前未知.
- 了解IgG4-RD中的PE对于诊断和管理至关重要.
研究的目的:
- 系统地审查和记录IgG4-RD.中多液 (PF) 和多组织的组织学和生物化学特征.
- 评估IgG4-RD患者的PE临床过程.
- 为了确定PE在这个人群中最有效的治疗方法.
主要方法:
- 进行了PRISMA系统的文献搜索.
- 包括在内的文章描述了IgG4-RD中的PE特性和管理.
- 抽取并分析了多液,多组织,临床过程和治疗的数据.
主要成果:
- 分析了46篇文章,涉及55名患者.
- 在大多数情况下,PE主要是右侧或双侧,血清性排泄物,淋巴细胞占主导地位,腺脱氨酶 (ADA) 升高.
- 在95.6%的病例中,肺部活检证实了IgG4-RD;在92.7%的患者中,皮质类固醇治疗是有效的.
结论:
- 患有IgG4-RD和PE的患者通常是50岁以上的男性,患有小/中度,单侧或双侧输液.
- 胸腔液通常是淋巴细胞排泄物,具有较高的ADA;活检有助于诊断.
- 皮质类固醇,有或没有免疫抑制剂,通常是有效的治疗方法.
相关概念视频
01:28Pleural Effusion II: Symptoms and Management
268
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
268
01:25Pleural Effusion I: Introduction
1.8K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
1.8K
01:30Pleural Disorders: Types and Brief Description
294
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
294
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.6K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.6K
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.9K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.9K
01:29Pneumonia II: Pathophysiology
556
The pathophysiology of pneumonia involves the following steps:
556