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Updated: Sep 11, 2025

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在治疗急性淋巴细胞白血病时,德西的作用机制

Xiaohui Gao1, Hui Zeng2, Fei Sun1

  • 1Department of Pediatrics, The Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.

Frontiers in medicine
|August 14, 2025
PubMed
概括

德西塔 (DAC) 通过向PTEN和4EBP1通路,有效地抑制急性T型急性淋巴细胞白血病 (T-ALL) 细胞生长,并促进细胞亡. 这种表观遗传疗法与多克索鲁比辛相比,显示出更高的抗白血病活性.

关键词:
在4EBP1中.在这里,我们可以使用PTEN.急性淋巴细胞白血病急性淋巴细胞白血病德西巴因 (decitabine) 是一种药物.瘤的生长 瘤的生长

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