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Updated: Sep 11, 2025

Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry
05:45

Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry

Published on: June 8, 2021

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矩阵辅助激光溶解离子化质谱检测人类血红蛋白α/β链变化:一项探索性研究

Dan-Ping Liu1, Bi-Cheng Yang1, Qiao-Yun Huang2

  • 1Jiangxi Key Laboratory of Birth Defect Prevention and Control Jiangxi Maternal and Child Health Hospital Nanchang China.

Analytical science advances
|August 14, 2025
PubMed
概括

这项研究引入了一种直接矩阵辅助激光吸附离子化飞行时间质谱法 (MALDI-TOF-MS) 方法,用于分析人体全血. 血红蛋白中的α/β-环球蛋白链比可以表明血病亚型.

关键词:
血液样本 血液样本血红蛋白链中的血红蛋白.人类血红蛋白的人类血红蛋白质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量矩阵辅助激光脱吸电离化离子化.泰拉塞米亚症是一种疾病.

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