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温暖的温度调节andrographolide生物合成通过雅斯蒙酸信号传递通过ApMYC2-ApHSFB2b模块在Andrographis paniculata中介导的雅斯蒙酸信号传递
Huiling Huang1,2,3,4, Qi Qi2, Zhenluan Yang1,2,3
1School of Pharmaceutical Sciences/State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
The Plant journal : for cell and molecular biology
|August 14, 2025
概括
温暖的气温可以促进Andrographis paniculata的生长和andrographolide (AD) 的产生. 这由通过ApMYC2-ApHSFB2b模块的斯酸信号调节,影响植物新陈代谢.
科学领域:
- 植物生物学 植物生物学
- 分子生物学分子生物学
- 生物化学 生物化学
背景情况:
- 安德罗格拉菲斯 (Andrographis paniculata) 产生的安德罗格拉菲尔 (AD) 是一种具有抗炎和抗菌性能的化合物.
- 温度对A. paniculata发育和AD积累的影响尚不清楚.
- 高温是A. paniculata.原生息地特征之一.
研究的目的:
- 研究温度对A. paniculata生长和AD生物合成的影响.
- 为了阐明调节AD产生的分子机制,以应对温度.
- 了解温度如何影响植物中的类代谢.
主要方法:
- 使用了代谢和转录组分析.
- 研究了转录因子ApMYC2和ApHSFB2b的作用.
- 研究了斯蒙酸 (JA) 信号通路组件与AD生物合成之间的相互作用.
主要成果:
- 温暖的温度促进了植物的生长,并增加了A. paniculata.中的AD积累.
- 转录因子ApMYC2和ApHSFB2b是AD发生的关键调节者.
- 温暖的温度增加了JA的积累,通过ApMYC2-ApHSFB2b模块激活ApCPS1的表达.
- 雅斯蒙酸ZIM域 (JAZ) 蛋白 (ApJAZ1,ApJAZ9) 与ApMYC2相互作用,调节ApCPS1的激活.
结论:
- 一个依赖温度的机制调节了A. paniculata.中的AD生物合成.
- 受JA信号影响的ApMYC2-ApHSFB2b模块是该规则的核心.
- 这些发现提供了关于温度在调节植物类代谢中的作用的见解.
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