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在前运动皮层神经元之间逐渐转移的共调模式在执行行动和观察期间携带动态上类似的信号
Zhonghao Zhao1, Marc H Schieber1,2,3
1Department of Biomedical Engineering, University of Rochester, Rochester, United States.
运动前皮层中的镜像神经元在执行行动和观察期间显示出不同的神经活动模式. 新的方法揭示了潜伏动态中的部分对齐,表明了共享的表示关系.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 认知神经科学 认知神经科学
背景情况:
- 运动前皮层中的镜像神经元在执行和观察动作时调节发射.
- 之前的研究表明,放电是一致的,但许多镜像神经元显示出非一致的活动.
- 达到运动的研究揭示了执行和观察期间共享和独家的神经子空间.
研究的目的:
- 开发一种新的方法来检查前运动皮层中复杂的手动 (伸手,抓住,操纵) 中的神经共调模式.
- 研究神经动态在行动执行和观察期间的特异性和对齐性.
- 分析镜像神经元和非镜像神经元的共同调制一致性.
主要方法:
- 开发了一种分析瞬间神经子空间时间序列的新方法.
- 在瞬间子空间之间计算的主要角度.
- 在执行和观察到达,抓取和操纵任务时,采样和投射的轨迹段进入瞬间子空间.
主要成果:
- 即时的神经子空间在执行和观察期间大多是不同的.
- 执行和观察期间的潜态动态显示通过正统相关性实现了部分对齐.
- 镜像神经元表现出一致的共调,而非镜像神经元在执行过程中表现出很高的变化.
结论:
- 执行行动和观察的神经动态在很大程度上是不同的,但有一些潜在的组织原则是共同的.
- 这些发现挑战了对复杂的手部运动高度一致的镜像神经元活动的概念.
- 在执行过程中非镜像神经元活动的变化需要进一步调查它们的作用.
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