三角化数据来定义患者的途径,诊断和治疗模式,以及在德国深静脉血栓症癌症患者的结果:混合方法的真实世界数据研究研究
Vanessa Colonna1, Rupert Bauersachs2, Roman Gerlach3
1Faculty of Medicine, Institute for Medical Information Processing, Biometry, and Epidemiology, Ludwig-Maximilians-University, Munich, Germany.
概括
巴伐利亚的癌症患者患深静脉血栓症 (DVT) 的风险很高,导致并发症和死亡率增加. 农村患者在获得专业护理方面面临挑战,这凸显了改善预防和治疗策略的必要性.
科学领域:
- 在瘤学瘤学.
- 血管医学 血管医学
- 公共卫生 公共卫生
背景情况:
- 德国的癌症发病率正在上升,癌症相关深静脉血栓症 (DVT) 的负担正在增加.
- 关于患者数量,癌症类型,医疗保健准入和癌症相关DVT的结果的强有力的区域数据很少.
- 本研究使用巴伐利亚的多源方法解决了这些数据缺口.
研究的目的:
- 分析巴伐利亚州癌症相关的DVT的发病率,特征和结果.
- 评估与癌症相关的DVT的农村患者的医疗保健准入和旅行时间.
- 为改善预防,诊断和治疗策略提供证据.
主要方法:
- 使用来自巴伐利亚法定医疗保险医生协会和AOK Bayern的索赔数据 (2016-2018) 进行混合方法分析.
- 纳入标准:年龄大于18岁,活跃的癌症诊断 (ICD-10-GM C00-C99) 和发生的血栓形成 (ICD-10-GM I80-I82).
- 一项补充的患者调查记录了农村患者的护理准入和旅行时间.
主要成果:
- 在677,327名巴伐利亚癌症患者中,38,393人 (6%) 患有DVT.
- 在皮肤癌 (30%),乳腺癌 (16%),以及消化器官 (16%),DVT最常发生.
- 并发症包括肺栓塞 (9%) 和慢性静脉疾病 (23%). 患有DVT的癌症患者的死亡率为23%,而没有DVT的癌症患者的死亡率为9%.
- 农村患者报告说,前往专门中心的平均行程时间为53分钟.
结论:
- 与癌症相关的血栓形成显著增加了发病率和死亡率.
- 高度的并发症和死亡率,加上农村地区有限的专业护理,需要有针对性的干预措施.
- 迫切需要基于证据的预防,护理协调和教育策略.
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