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Updated: Sep 11, 2025

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

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一个更有效的动态编程算法来设计编码序列,通过共同优化其结构稳定性和Codon使用情况来设计

Yan-Ru Ju, Long-Shang Cho, Chin Lung Lu

    IEEE transactions on computational biology and bioinformatics
    |August 14, 2025
    PubMed
    概括

    我们开发了LinearCDSfold,这是一种用于设计编码序列 (CDS) 的新型动态编程算法,可以优化二级结构稳定性和编码子适应指数. 这种方法提供了准确和高效的CDS设计,在速度方面超过现有工具.

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