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Updated: Sep 11, 2025

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay
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Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay

Published on: October 30, 2015

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从使用图形神经网络的结构中预测TCR-pMHC绑定特异性

Jared K Slone, Anja Conev, Mauricio M Rigo

    IEEE transactions on computational biology and bioinformatics
    |August 14, 2025
    PubMed
    概括

    预测T细胞受体 (TCR) 和-MHC (pMHC) 相互作用是癌症免疫治疗的关键. 一个新的基于图形的机器学习模型,STAG,使用3D蛋白质结构来准确预测TCR-pMHC结合.

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