与中风复发和缺血性和出血性中风死亡率相关的因素:系统审查和元分析的议定书
Simone Ryan1,2, Katie Robinson1,2,3, Rose Galvin1,2,3
1School of Allied Health, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland.
PloS one
|August 14, 2025
概括
本系统性审查确定了中风复发和死亡率的临床和生活方式风险因素. 了解这些因素对于改善二次中风预防策略和患者治疗结果至关重要.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 脑卒中是全球死亡和残疾的主要原因之一.
- 卒中幸存者面临复发的高风险,风险因素不明.
- 现有的评论受到年龄,地理或重点的限制.
研究的目的:
- 系统地确定中风复发和死亡的临床和生活方式风险因素.
- 综合有关影响二次中风事件的因素的证据.
- 为改善二次中风预防指导方针提供信息.
主要方法:
- 在PubMed,EMBASE,CINAHL,PsycINFO和灰色文献中进行系统搜索.
- 包括对成人缺血性和出血性中风的前性队列研究.
- 数据提取,偏差风险评估 (ROBINS-E) 和证据确定性评估 (GRADE).
主要成果:
- 临床因素的分析 (例如高血压,心房动).
- 评估生活方式因素 (如体育活动,营养,吸烟).
- 超分析 (随机效应模型) 或发现的叙事综合.
结论:
- 重复性中风导致死亡率增加和预后较差.
- 识别风险因素有助于制定有针对性的二次预防.
- 这一审查支持加强对中风幸存者的临床指导.
相关概念视频
Regulation of Stroke Volume
3.5K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
3.5K
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
1.4K
Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
1.4K
Factors affecting Blood pressure
4.8K
Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
Physiological Factors:
4.8K
Ischemic Heart Disease: Overview
1.4K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.4K


