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在ART中断期间的治疗性CD8+T细胞组织保留和免疫调节无法防止SIV反弹

M Betina Pampena1,2, Sadia Samer3, Elise G Viox3

  • 1Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.

Proceedings of the National Academy of Sciences of the United States of America
|August 14, 2025
PubMed
概括

在淋巴组织 (LT) 中保留T细胞并不能在停止抗逆转录病毒治疗 (ART) 后防止病毒反弹. 即使增强了免疫功能,局部的CD8+ T细胞也无法在分析性治疗中断 (ATI) 期间控制 Simian 免疫缺陷病毒 (SIV) 复制.

关键词:
艺术 艺术 艺术 艺术CD8+ T 细胞 CD8+ T 细胞这就是SIV SIV.免疫调节 免疫调节 免疫调节淋巴结中的淋巴结.

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