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Updated: Sep 11, 2025

Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43
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孔-C 测序识别了以插件驱动的染色体构造干扰,使肺炎球菌表观遗传变异区分开来

Tze Yee Lim1, Samuel T Horsfield1,2, Catherine M Troman1

  • 1MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom.

PLoS pathogens
|August 14, 2025
PubMed
概括

肺炎链球菌表现出与移动遗传元素相关的全基因组DNA甲基化变化. 这些变化影响染色体结构,但异源性沉默不是一个因素,异质性来自于随机移动遗传元素活动.

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