在沉积在沉积物-水界面时重塑塑层中的抗生素耐药性基因:动态进化和传播机制
Yufang Chen1, Shiqi Liu1, Tian Ouyang1
1State Key Laboratory of Water Cycle and Water Security, Hohai University, Nanjing 210098, China; College of Environment, Hohai University, Nanjing 210098, China.
Journal of hazardous materials
|August 14, 2025
概括
微塑料 (MP) 为微生物创造了独特的息地,影响了抗生素耐药性基因 (ARG). 沉积物-水界面 (SWI) 在MP相关的微生物群落中显著改变了ARG的丰富性和转移.
科学领域:
- 环境微生物学 环境微生物学
- 环境化学环境化学
- 生态毒理学 生态毒理学
背景情况:
- 微塑料 (MP) 创造出独特的微生物息地,称为塑,可以丰富抗生素耐药性基因 (ARG).
- 在MP运输过程中,特别是在沉积物-水界面 (SWI) 时,ARG在塑层中的行为和演变尚未得到充分理解.
研究的目的:
- 调查ARG在塑圈社区的动态变化和潜在机制,随着MP跨越SWI.
- 为了比较可生物降解的聚乳酸 (PLA) 和不可生物降解的聚乙烯二甲 (PET) 塑料球中的ARG动态.
主要方法:
- 在深水和SWI的PLA和PET塑球中对ARG的丰富性和多样性的比较分析.
- 评估微生物社区结构,相互作用和水平基因转移潜力.
- 研究功能反应,包括氧化应激和代谢途径.
主要成果:
- 在深水中,PLA塑球的ARG含量高于PET. 在深水中,PLA塑球的ARG含量高于PET.
- 在SWI中,PET塑料球在ARG中显著增加 (45.71-65.10%),而PLA塑料球显示下降 (52.15-53.25%).
- 在SWI的塑球具有更高的物种丰富性,多样性和更复杂的微生物相互作用,对PET和PLA的水平基因转移有明显的影响.
结论:
- SWI在调节移动塑球内的ARG传播方面发挥着至关重要的作用.
- 氧化应激反应,细胞膜透性和能量代谢等机制参与控制ARG增殖.
- MP类型 (生物降解性与非生物降解性) 在沉积过程中显著影响ARG动态.
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