一个细菌的垃圾是另一个细菌的宝藏
Samuel C Syberg1, Lauren J Rajakovich1
1Department of Chemistry, University of Washington-Seattle, 4000 15(th) Avenue NE, Seattle, WA 98195, USA.
Cell host & microbe
|August 14, 2025
概括
人体肠道细菌可以通过共享资源进行合作. 一项新的研究揭示了两种共生细菌物种利用一种新的交叉养途径来代谢饮食中的抗氧化剂.
科学领域:
- 微生物学 微生物学
- 人类肠道微生物组
- 代谢途径 代谢途径
背景情况:
- 肠道微生物传统上被视为营养素的竞争对手.
- 新出现的证据表明,肠道细菌之间有合作的资源共享.
- 饮食中的化合物可以影响微生物的新陈代谢和相互作用.
研究的目的:
- 研究不同肠道细菌物种之间的合作代谢相互作用.
- 通过开始性细菌识别营养利用的新途径.
- 了解饮食中抗氧化剂在微生物交叉养中的作用.
主要方法:
- 利用微生物共同培养实验.
- 使用代谢分析来追踪化合物分解.
- 确定了参与该途径的特定酶和基因.
主要成果:
- 发现了一种新的交叉养途径,涉及两种共生细菌物种.
- 通过这种途径证明了饮食中抗氧化剂的代谢.
- 描述了细菌之间特定的资源共享机制.
结论:
- 肠道细菌参与复杂的合作代谢活动.
- 交叉养途径对于营养共享和微生物社区功能至关重要.
- 饮食成分可以通过肠道中复杂的微生物相互作用来处理.
更多相关视频
02:55Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention
Published on: October 6, 2023
1.5K
12:47Workflow Based on the Combination of Isotopic Tracer Experiments to Investigate Microbial Metabolism of Multiple Nutrient Sources
Published on: January 22, 2018
9.5K
相关概念视频
Symbiosis
30.7K
Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
30.7K
Microbial Nutrition
292
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
292
The Roles of Bacteria and Fungi in Plant Nutrition
41.0K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
41.0K
Environmental Applications of Microorganisms
242
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
242
Epiphytes, Parasites, and Carnivores
13.2K
Plants often form mutualistic relationships with soil-dwelling fungi or bacteria to enhance their roots’ nutrient uptake ability. Root-colonizing fungi (e.g., mycorrhizae) increase a plant’s root surface area, which promotes nutrient absorption. While root-colonizing, nitrogen-fixing bacteria (e.g., rhizobia) convert atmospheric nitrogen (N2) into ammonia (NH3), making nitrogen available to plants for various biological functions. For example, nitrogen is essential for the...
13.2K
Amino Acid Catabolism
189
Microorganisms rely on proteins as an essential carbon and energy source, particularly in environments with limited polysaccharides or lipids. However, proteins are too large to cross the plasma membrane unaided, necessitating enzymatic degradation. Microbes secrete extracellular proteases and peptidases that hydrolyze proteins into peptides, which can then be transported across the membrane. Once inside the cell, intracellular proteases degrade these peptides into free amino acids, which...
189
