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Updated: Sep 11, 2025

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神经发育障碍在交换因子DENN/MADD中的突变破坏了Rab GTPases的激活

Maleeha Khan1, Rahul Kumar1, Jean-François Trempe2

  • 1Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montréal, Quebec, Canada.

The Journal of biological chemistry
|August 14, 2025
PubMed
概括

这项研究确定了新的Rab GTPase对DENN/MADD蛋白的相互作用,这对于膜贩运至关重要. 这些相互作用的干扰与人类疾病有关,突出显示DENN/MADD.

关键词:
DENN/MADDD 在线播放拉布GTPases是一种GTPase.细胞生物学 细胞生物学遗传病是一种遗传性疾病.关氨酸核酸交换因子 (GEF)影像成像技术 影像成像技术膜贩运 贩卖 贩卖 贩卖 贩卖 贩卖 贩卖神经发育障碍是一种神经发育障碍.蛋白质与蛋白质的相互作用

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